BACKGROUND Conventional fluorescent dyes used in nucleic acid detection methods suffer from a number of limitations. High backgrounds result in false positives and a reduction in sensitivity. The smal..
BACKGROUND Enzymes, especially proteases play essential roles in disease specific processes and are valuable targets for therapeutic intervention. A number of methods of targeting enzymes have been us..
Background:
Ageing populations coupled with failings in current drug based therapies are driving the quest for new treatments and methods of disease management. One of the most promising advances tow..
The Invention Transgenic Kenaf plants (Hibiscus cannabinus L.) have been developed by modifying the endogenous concentration of gibberellins using anti-sense technologies. These novel Kenaf plants h..
Background: Anti-oxidant and anti-aging compounds have been screen using other animal models. However, there was no clear understanding of the molecular basis for how the screening worked and the sys..
Background: Over the past 25 years, the Wallace's laboratory discovered that the variation in the maternally-inherited human mtDNA forms a single mtDNA tree in which the branches of the tree are regi..
Background: Currently the critical storage of bio-degradable tissue for long periods of time is done at -70" C. This temperature does provide nearly unlimited storage time. Storage at -70' C is subst..
Background: In biomedical research, controlled modulation of physiological functions of various excitable cells such as skeletal, cardiac and neuronal cells is important. The information derived from..
Background: It is becoming increasingly clear that mitochondrial DNA (mtDNA) base substitution mutations are a common cause of age-related degenerative diseases as well as cancer. However, no mouse m..
Background: In clinical applications for the examination of cardiovascular, cerebrovascular, leg and other vessels, ultrasound imaging (USI) and optical coherence tomography (OCT) are two of the most..
Background: Currently, X-ray mammography is the widely accepted method for the detection of changes in the breast that may be cancer. However, this screening technique lacks specificity to determine ..
Background: During genetic testing of the human MLHl and MSH2 genes, missense variants are sometimes encountered. It is difficult to tell if these variants are benign or deleterious. Technology: T..
Background: Acne vulgarisis the most common skin disorder, and while it usually appears in adolescence, adults can get it too. The pathogenesis of acne is complex and multifactorial. According to the..
Background: Bone Morphogentic Proteins (BMP)s are involved in various developmental processes, but are most famous for the activity to stimulate bone formation. Technology: Through phylogenetic fo..
Background: Manipulation of microscopic objects by laser methods has been used since the 1970s. Both laser tweezers (used to hold microscopic objects in place) and optical scissors (used to conduct d..
Background: Use of instruments to assess etiology and status of chronic wounds is still in an embryonic state. Clinicians rely primarily on clinical features such as wound size, location, depth, and ..
Background: Current technologies used to develop novel protein and antibody libraries have been met with limited success. Specified and controlled distribution of mutations relative to the parent pro..
Background: Cardiac catheterization is typically performed with stiff-tipped catheters. In order to engage a blood vessel orifice, the stiff tip must be positioned at a precise location, and in the c..
Background: Chemical cytometry involves the use of high-sensitivity analytical tools, such as mass spectrometry, electrochemistry and capillary or microfluidic separation methods to characterize sing..
Background: Asthma is a pulmonary disorder characterized by chronic airway inflammation and airflow obstruction that is widespread, but variable in space and time. Although airflow obstruction is rou..
Background: Mechanotransduction, the process by which cells convert mechanical stresses to a biochemical signal, influences many cell functions including cell motility and proliferation and also modu..
Background: Tracheal suction catheters used today by respiratory therapists have a number of drawbacks. First, the therapist operating the tracheal suction catheter is directly exposed to the patient..
Background: To date, cell lysis in microfluidic devices for analytical purposes has been achieved using chemical, electrical, and optical means. Chemical cell lysis occurs on time scales of several t..
Researchers at the University of Michigan have developed a double-clad photonic cystal fiber optic technology that could provide a significant performance improvement to existing lines of endoscopes a..
Background: Microelectrical-mechanical systems (MEMS) are miniature mechanical devices intended to perform non-electronic functions such as sensing or actuation. These devices are typically built fro..
Background: The laser scanning confocal microscope (LSCM) is widely used as a confocal microscopy technique for imaging fluorescent objects in a manner that removes out of focus fluorescent light and..
Background: Tinnitus is the perception of sound in the absence of corresponding external sounds. Although known for its high-pitched ringing, tinnitus is an internal noise that varies in pitch and fr..
Background: "Molecular Electronics" (ME) generally refers to a class of novel electronic devices in which the electronic response and function are entirely controlled by single molecules. In principl..
Background: PK2 belongs to a family of secreted peptides that regulate diverse biological functions including serving as a regulatory molecule for circadian rhythms. The signaling of PK2 is mediated ..
Background: The ability to deliver drugs locally to the site of need and over a prolonged period of time is important as a therapeutic method for many ailments and diseases. Many drugs are more effec..
Background: The use of wide-field, broadband, spatially illuminated imaging of turbid media has the potential for simultaneous surface and sub-surface mapping of media structure, function and composi..
Background: Optical coherence tomography (OCT) is a non-invasive sub-surface optical imaging modality with high axial resolution and high signal to noise ratio compared to other imaging modalities su..
Background: Sjogren's Syndrome is a grave autoimmune disease in which destruction of the exocrine glands leads to severe dryness of the eyes and mouth, with additional systemic complications. The pat..
Background: Correlation of brain images and genotypes for diagnostics of neuropsychiatric disorders and drug discovery Technology: The invention includes general methods for identifying markers th..
Background: Positron emission tomography (PET) is a non-invasive test that helps doctors diagnose abnormalities, determine the extent of disease, prescribe treatment, and track progress. The patient ..
Background: An important issue in laser treatment of cutaneous lesions is to protect the epidermis from thermal damage. This heating, which is primarily caused by light absorption in the melanosomes,..
Background: Respiratory complications are the most common cause of morbidity and mortality following spinal cord injury. Patients with such injuries often suffer a disruption in the neuromuscular cen..
Background: Conventional charged particle imaging sensors use film and charged couple device (CCD). CCD has poor radiation tolerance and records images indirectly while the film is an analog recorder..
Background: CRAC stands for Ca2+-Release Activated Ca2+. When Ca2+ from the endoplasmic reticulum (a major store of Ca2+) is depleted, a CRAC channel, is activated to slowly replenish the endoplasmic..
Background: Diabetes Mellitus (DM) is one of the leading causes of death in the United States (Bassett). The molecular defects underlying the development of most human Type 2 DM are not yet clear. Bu..
Background: In performing, through an anatomical channel inside the body, a diagnostic or surgical procedure, the surgeon or operator may need to rotate with precision the distal end inside the body,..
Background: The BioEnterics Intragastric Balloon System™ is a non-surgical, non-pharmaceutical alternative for the treatment of obesity. The balloon system is designed to provide loss therapy to re..
Background: The determinant factor for the successful applications of delivering drugs is to develop a non-viral and efficient carrier. Cationic lipid based liposomal carriers are the most attractive..
Background: It has been reported that the concentration of Nitric oxide (NO) in the exhaled breath was substantially elevated in patients with asthma who were not treated with corticosteroids, sugges..
Background: It has been well recognized that the tissue stiffness plays an important role for diagnosis of breast cancers, as tumors are stiffer than the surrounding breast tissues, and malignant tum..
Background: It has been well recognized that the tissue stiffness plays an important role for diagnosis of breast cancers, as tumors are stiffer than the surrounding breast tissues, and malignant tum..
Background: Keratoconus is a noninflammatory progressive corneal thinning disorder leading to mixed myopic and irregular astigmatism and is implicated as a major cause of cornea transplants in the We..
Background: Large scale confinement chambers have been created in the past using traditional glass-blowing techniques. However, conventional glass-blowing can only be used to create large components ..
Background: Most of the current techniques used for Dielectrophoresis separation use planar electrodes which sit at the bottom of the channel. With this design the electric field decreases dramatical..
Technology: University of California researchers are investigating a protein scaffold system for molecular transport, namely, the E2 protein of Bacillus stearothermophilus in the pyruvate dehydrogena..
Background: The pathological protein aggregates such as beta-amyloids, alpha-synuclein and prion protein deposits in the CNS can be removed by vaccination, i.e., immunization using specific antibodie..
Background: Large scale confinement chambers have been created in the past using traditional glass-blowing techniques. However, conventional glass-blowing can only be used to create large components ..
Background: In the chemical, biomedical, and pharmaceutical industries, it has become increasingly desirable to perform large numbers of chemical operations in a highly parallel fashion. For example,..
Background: Cornelia de Lange Syndrome (CdLS) is a moderately common multisystem birth defects disorder that poses severe medical and social challenges for affected children and their families. Diagn..
Background: Sodium/potassium ATPases (Na+/K+-ATPases), a family of multi-subunit ion pumps, are the most important active transporters in animal cells. They are required for maintaining the electroch..
Background: Numerous methods and devices are available to detect and/or quantify target DNA in a test sample. In almost all of these methods, detection and/or quantification are performed utilizing a..
Background: In many neurodegenerative diseases and in spinal cord injury, axons and synapses are damaged; a cell culture model is useful for investigation into these areas of research. In typical cel..
Background: Adherence is one of the pivotal determinants of treatment outcomes for many medical disorders. It is estimated that 50% or more of patients with chronic conditions are noncompliant with m..
Background: Full length Lymphoid Enhancer Factor-1 (LEF-1) is a transcription factor that promotes cell growth via its interaction with the WNT signaling mediator beta-catenin. Truncated LEF-1 lacks ..
Background: Lamin-5, a protein produced by skin, mammary and other epithelial cells, may be involved in the progression of cancer. Purified human laminin-5 is not commercially available, and we have ..
Background: In the past decade, droplets have been intensively used by the industries as an agent for drug preparations, for plastic polymerizations, and chemical processing. Recent advancements in m..
Background: In patients suffering from multiple sclerosis (MS) B cells, stimulated by axon antigens, infiltrate central nervous system. Technology: The inventors discovered a new class of antibodi..
DOMAIN Aging of injuries on a victim’s body is an important aspect of forensic medicine. Currently, visual assessment and colorimetry based on empirical criteria are the most common techniques for t..
DOMAIN Although the incidence of gastric carcinoma (tumour in stomach) is declining, this disease is still the second most frequent cause of cancer death worldwide. Gastric carcinomas are often not de..
DOMAIN The mucosal surfaces of the body (such as GI tract, respiratory tract, eye, and genitourinary tract) constitute the major target for drug and gene delivery. As such, mucous secretions can have ..
DOMAIN The study of gene expression in cells is increasingly being used to understand their biological function. The genes are up- and down-regulated by a complex protein regulatory network, which res..
Background: For microfluidic applications, different electrodes inside the microfluidic channels may be patterned by metal evaporation methods such as thermal evaporation, electric beam evaporation, ..
Background: A disadvantage of closed microfluidic channels are that they are made from different materials. Also, most of the microchannels are fabricated from lithography techniques which require th..
DOMAIN In many situations it would be beneficial to have an instrument that can show In biology and medicine, fluorescent labelling is used to detect the location and concentration of various molecule..
In many situations it would be beneficial to have an instrument that can show directly the spatial distribution of various chemical components in real time of a surface. Typical application areas are ..
Background: Optical coherence tomography (OCT) has been used for high resolution optical imaging in many areas of medicine, especially ophthalmology. "Conventional wisdom" was that OCT could not be d..
DOMAIN An early and accurate detection of cerebral palsy (CP) enables correct treatment at an early age to the infant at risk. Today’s methods for detecting CP are unable to establish a diagnosis un..
Categories: Pharmaceuticals: Central Nervous System Disorders, Immune and Inflammatory Disorders Biotechnology: Assays, Diagnostics, Model Systems
Background: Mgat5 is an enzyme that glycosylat..
DOMAIN Within an ageing population, ischemic heart disease (IHD) and secondary heart failure represent major challenges underlining a demand for diagnostic imaging to identify IHD in its different sta..
Background: The highly abundant GTP binding protein elongation factor Tu (EF-Tu) fulfills multiple roles in bacterial protein biosynthesis. EF-Tu also binds other ligands, including four structurally..
Background: Auditory prostheses using microelectrode arrays suffer from a number of limitations. Issues that were not resolved are electrode size, the need for electrical wires to communicate with an..
Determining the severity of a leakage through a heart valve is important. There are several parameters that are clinically interesting in this regard: the area of the lesion, the flow or flow rate thr..
DOMAIN Glycosylases have found use in a number of methods aimed at analyzing DNA for the presence of altered nucleobases that could result from ionizing radiation or chemical oxidants, identifying mis..
Background: Researchers estimate that 80% of all machine failures are due to wear and that 1.3~1.6% of the GNP is lost to degradation of machinery due to friction-related wear. The abnormal abrasive ..
Background: Today, most detection schemes for DNA, proteins and other large biomolecules involve luminescent measurements using a variety of labels (i.e. fluorescent and/or chemiluminescent probes, p..
Recent attention has focused on high aspect ratio carbon micro-electromechanical (C-MEMS) because of the many applications possible, such as micro-electrodes in electromechanical sensors and miniaturi..
Background: Exhaled nitric oxide (NO) arises from both airway and alveolar regions of the lungs, which provides an opportunity to characterize region-specific inflammation. Current methodologies rely..
Background: Total ankle arthroplasty (TAA) is the process of replacing a diseased ankle with a prosthetic ankle. Over the years there have been several efforts to provide a total ankle replacement sol..
Background: Measuring temperature in tissue is highly relevant to treatments applied to tissue in which the tissue becomes heated. This includes methods that treat tissue with RF (Radio Frequency) su..
Background: Microscopy is an important tool used by all researchers in the scientific community. Often, a microscope user will first scan the specimen with a low power dry objective and then wish to ..
Background: Preservation of posttranslational modifications during purification is crucial for successful mass spectrometric analyses of protein modifications. Current tandem-affinity purification st..
Background: UC Case No.: 2004-692 Patent Application Publication No.: WO/2006/017293 International Application No.: PCT/US2005/024697
This invention is an animal model and various cell-based mode..
Technology: The invention is on new polymeric biomaterials. The new biomaterials were created by chemical synthesis with carbohydrates and amino acids as building blocks. The biopolymers have a speci..
Background: Cell encapsulation is a highly useful tool in cell culturing, assay, and cell-based therapy applications. Encapsulation has traditionally been accomplished by extrusion through a nozzle, ..
Background: Diffuse optical spectroscopy (DOS) has been successfully employed for quantitative determination of in vivo optical properties and chromophore concentrations of deep tissues such as breas..
Background: Currently endodontic therapy is based upon radiographic information and tactile feedback. Direct detection and localization of infected dentin and pupal tissue has not been possible. It h..
Background: Antioxidant and xenobiotic metabolizing enzymes are critical in the protection against chemically induced oxidative/electrophilic stress in cells that cause damage, DNA mutation, apoptosi..
Background: Amphiphilic compounds are of general interest in numerous disciplines in life sciences, especially in pharmacology and general chemistry, and numerous amphiphilic compounds are known in t..
Background: Options for successful repair of peripheral nerves after traumatic injury remain suboptimal. Current strategies are limited to transfer of donor nerves from functional areas, with substan..
Background: Diabetes is a condition that affects blood vessels throughout the body, particularly in the kidneys and eyes. Diabetic retinopathy is a complication of diabetes and is the leading cause o..
Background: Controlling the chemistry of small drops is troublesome owing to the difficulty in handling and metering small volumes. To change the chemistry of a 50nl drop by 10% would require adding ..
Background: Biochips can be used in vitro or in vivo to deliver small, controlled amounts of chemicals or other molecules at controlled times and rates. Current delivery release mechanisms include el..
Background: Cutaneous vascular lesions including port wine stains (PWS) and hemangiomas are frequently treated with laser and light devices. The pulsed dye laser (PDL) is the current standard means o..
Background: Patent "WO02/31145" discloses a newly deorphanized GPCR system, Neuropeptide S (NPS), the endogenous ligand, and its cognate GPCR. However this patent does not detail the pharmacological ..
Background: In many disciplines, quantitative measurements of color are required to evaluate nondestructively the state of an object (e.g., quality of produce). This characterization is typically per..
Background: For a typical MEMS switch, the resonant frequency is around 20 to 30 GHz which can not be employed by commercial wireless systems operating at a frequency band of 2 to 8 GHz. This resonan..
Background: Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent disorder of early childhood. It affects an estimated 3-6% of elementary school children. ADHD consists of development..
Background: Amphiphilic vesicles are artificial cells with applications in drug delivery (including biomolecular nanomedicine such as DNA, peptides, proteins), combinatorial chemistry, nanoscale chem..
HSV keratinitis is characterized, in part, by scarring of the eye as a result of HSV reactivation. To date, corneal transplantation is the standard treatment method. A significant obstacle preventing ..
Background: One of the great limitations in spine surgery is the difficulty with removing bone without damaging adjacent soft structures (such as the spinal cord, nerves, and durra). This difficulty ..
Background: The volume of O2 consumption (VO2) and the volume of CO2 production (VCO2) can give vital information about a patient under anesthesia. For example, monitoring VO2 can detect non-steady s..
Background: The volume of O2 consumption (VO2) and the volume of CO2 production (VCO2) can give vital information about a patient under anesthesia. For example, monitoring VO2 can detect non-steady s..
Background: Trichomoniasis is a venereal disease of cattle caused by a protozoan parasite, Tritrichomonas foetus. The disease has been reported worldwide with an estimated economic loss to the U.S. b..
Background: Ten percent of the general population suffers from hearing loss and that number rises to thirty five percent for people over sixty-five years of age. However, current digital hearing aids..
University of California, Irvine researchers have discovered a method to design and use selective inhibitors against a family of nitric oxide synthetase isoforms that control the production of nitric ..
Background: The ability to assess the health and condition of bone tissue is important since bone tissue viability is closely linked to composition, structure, and physiology. Traditional methods for..
Background: There exists a need for thick artificial tissues to cover large tissue defects following trauma or surgical resection of tumor. The primary limitation in the design of these tissues as we..
University of California, Irvine researchers have discovered SKCa3-1b and SKCa3-1c, two novel isoform variants of the SK3 (also known as KCNN3) gene. The SK3 gene is located on human chromosome 1q21 i..
Background: Cervical cancer is one of the leading causes of cancer-related death in women worldwide. Approximately 500,000 new cases are diagnosed each year and pre-cancerous abnormalities of the cer..
Background: Ectopic activation of the Wnt signaling pathway leads to increased cellular growth and division in experimental organisms and mutations in the Wnt pathway. Wnt pathway genes are tightly l..
Thrombin is an enzyme in the blood that plays a key role in platelet formation during injury. While blood coagulation is essential for a surface wound, platelet activation underlies various pathologic..
Background: Recently, activation of the P2Y12 G-protein coupled receptor (GPCRs) has been shown to be central to platelet aggregation. Drugs preventing platelet aggregation are being tested, but one ..
Background: In the pharmaceutical industry, synthetic chemists often alkylate starting compounds to generate compounds that have more desirable properties. However, the current reagents used in this ..
Background: Jaagsiekte sheep retrovirus (JSRV) causes broncheolo-alveolar carcinoma in sheep and is a significant veterinary problem world-wide. Clinically and histopathologically, this disease has s..
During heart transplantation, the heart must be preserved while it is transported from donor to recipient. Standard techniques call for the heart to be immersed and cooled in cardioplegia or saline so..
Background: Membrane associated heparin sulfate proteoglycans (HSPGs) have been shown to play important roles in many aspects of cell behavior, including cell-cell and cell-extracellular matrix adhes..
In the ongoing battle against the human immunodeficiency virus (HIV), researchers at the University of California, Irvine, have synthesized novel compounds that inhibit the protein HIV Integrase and p..
Scientists at the University of California, Irvine, have isolated a candidate gene that may be responsible for increasing the risk of schizophrenia and bipolar disorder. This elusive gene encodes for ..
Background: As the development of protein products and peptide mimetics becomes more prevalent in the biotechnology and pharmaceutical industries, the ability to mimic the protective and modulate the..
Background: The determination of oxygen consumption is an important monitor of normal cardiopulmonary and tissue function in anesthesia and critical care medicine. This requires accurate measurement ..
Background: The most common method for manufacturing polyolefins and their derivatives is by polymerization of olefin monomers with Ziegler-Natta catalysts or by the use of free radical, nucleophilic..
The present invention provides non-human, transgenic animals for use as a model for the study of Alzheimer's Disease. The animals exhibit pathology associated with Alzheimer's Disease. The phenotype i..
Currently, flow cytometry is the only method available for the purification of specific chromosomes.
The current flow cytometry method requires a long time to sort large quantities of cellular sta..
Background: L-Glutamate is one of the most abundant excitatory neurotransmitters in the mammalian brain and, as such, is responsible for many synaptic transmissions in the central nervous system. Yet..
The invention is directed to prognosis, diagnosis and treatment of autoimmune diseases, including SLE (systemic lupus erythematosus), type-1 diabetes, experimental allergic encephalomyelitis (EAE) and..
Background: Retrovirus vectors infect cells at high efficiency and are capable of integrating DNA copies of themselves into a host genome. Such vectors are, in many ways, desirable for introduction a..
Background Bone and ligament injuries present the greatest challenges in connective tissue regeneration. The design of materials for these applications lies at the forefront of material science and is..
APPLICATION OF TECHNOLOGY:
- Preparation of chiral, pharmaceuticals, or specialty organic compounds - Biosensor technology for medical, chemical and biological sensing
ADVANTAGES:
- Co-factors ar..
Berkeley Ergonomic Arm is a practical ergonomic intervention and support system to improve productivity and reduce work place ergonomic-related injuries. Berkeley Ergonomic Arm dynamically enhances mu..
Single dose drug therapy for preventing restenosis and reducing the effects of acute phase response
ADVANTAGES:
- Promises to help prevent restenosis and thereby reduce the frequency of repeated i..
APPLICATIONS OF TECHNOLOGY:
- Developing therapeutics for the radiosensitization of cancer cells - Assessing the efficacy of cancer treatments - Cancer drug screening and development - Research on t..
APPLICATIONS OF TECHNOLOGY:
- Creation of new lipid-reducing drugs - Large scale genetic screening of individuals for cardiovascular disease susceptibility - Delivery of the ApoAV protein to reduce ..
APPLICATIONS OF TECHNOLOGY:
- Semiconductor crystals - Magnetic materials
ADVANTAGES:
Low-cost, low-energy method works at room temperature
ABSTRACT: LBNL researchers, Deborah Charych and Ami..
PATENT SUMMARY: The present invention relates to methods and compositions for the diagnosis and treatment of cells lacking normal growth arresting characteristics. This characteristic is referred to ..
APPLICATIONS OF TECHNOLOGY:
Biosynthesis of carboxylic acids and lactones for biofuel production
ADVANTAGES:
- Provides biofuel alternatives to ethanol - The new enzymes can be modified to tailor..
AVAILABLE TECHNOLOGIES
Low-resistivity Photon-transparent Window Attached to Photo-sensitive Silicon Detector
APPLICATION OF TECHNOLOGY:
- Medical Imaging - Other Digital Scanning technologies
..
APPLICATIONS OF TECHNOLOGY:
- Molecular biology research - Medical research
ABSTRACT: Telomeres are believed to be critical regulators of the genome, and telomere stability important for preventin..
APPLICATIONS OF TECHNOLOGY:
- Screening all 24 chromosomes for numeric chromosome abnormalities during Preimplantation Genetic Diagnosis - Diagnosing disease states requiring cytogenetic analysis - M..
APPLICATIONS OF TECHNOLOGY:
Under a microscope, fluorescent markers (right) reveal amplified genes in the chromosomes of a breast tumor’s cells.
- Identifying patients with breast cancers that a..
PATENT APPLICATION ABSTRACT:
The present invention provides the design, synthesis and characterization of compositions comprising asymmetric bolaamphiphilic lipids that form extended polymeric ribbon..
APPLICATIONS OF TECHNOLOGY:
- Multinozzle electrospray emitters for proteome-on-a-chip - Mass spectroscopy of peptides and biomolecules with a wide range of weights - Process for fabricating comp..
APPLICATIONS OF TECHNOLOGY:
Converting plant lignocellulosic biomass to simple sugars for fermentation into biofuels, and hydrogen.
ADVANTAGES:
- Promises to be more energy and chemically efficie..
IB-2279
APPLICATIONS OF TECHNOLOGY:
• Digital imaging
• Digital cameras, image scanners, and pixelated detectors
• Applicable to visible, ultraviolet and infrared cameras
ADVANTAGES:
..
IB-2420
Dual PET-TRUS imaging co-registers positron emission tomography and transrectal ultrasound images taken during the same patient exam. The simulated “merged PET-TRUS image” (central imag..
IB-2186
Published in Nature, March 2008. See link below.
APPLICATIONS OF TECHNOLOGY:
Screening for metastatic-prone breast cancers
Using SATB1-specific inhibitors to treat breast cancer
..
IB-2023
Berkeley Lab's S3 cell lines display partial loss of differentiation in 3DirBM Cultures.
Human breast epithelial cell lines were derived from a patient with fibrocystic breast dise..
JIB-2395
APPLICATIONS OF TECHNOLOGY:
Development of new breast cancer therapies and diagnostic assays Researching cancer progression and remission
ADVANTAGES:
Specifically isolates human mamm..
JIB-2397
Press Release, Berkeley Lab, June 30, 2008
The dream of personalized medicine — in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profil..
EJIB-2540
APPLICATIONS OF TECHNOLOGY:
Biosynthesis of carboxylic acids and lactones for biofuel production
ADVANTAGES:
Provides biofuel alternatives to ethanol The new enzymes can be modi..
B-1944
APPLICATIONS OF TECHNOLOGY:
Developing therapies for treating bone related conditions such as osteopenia, osteoporosis, fractures, and sclerosteosis Diagnosing and treating Van Buchem’..
Abstract
The present invention provides a bacterium containing a unique plasmid. The plasmid is unique in its ability to replicate in both Gram positive and Gram negative bacteria. In addition, the ..
Description of the technology: Synthesis, characterization, and spectroscopy of upconverting lanthanide-doped NaYF4 nanocrystals (NCs). Monodisperse cubic NaYF4 NCs were synthesized via a thermal dec..
Microporous crystalline materials (e.g. zeolites, aluminophosphates), also called molecular sieves, are widely used as catalysts, adsorbents, and membranes. Two factors largely determine the utility o..
This monoclonal antibody is for one of the polypeptides of vertebrate cytoplasmic dynein. This antibody is an IgG and is therefore more useful than IgM; it is also prepared with mammal (cow) antigen, ..
General Information
Hydrocephalus is a condition where cerebrospinal fluid (CSF) in the brain accumulates in the ventricles and increases pressure within the skull. It is routinely treated through ..
Liquid-phase Reactor for Catalytic Production of Biomarkers from Biological Materials - A method for rapid identification of biological materials such as Anthrax.
General Information
In 2001, just..
